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Random assignment is the process by which researchers select individuals from their total sample to participate in a specific condition or group, such that each participant has a specifiable probability of being assigned to each of the groups or conditions. These different conditions or groups represent different levels of the independent variable. Random assignment is generally considered the most important criterion to qualify a research design as an experimental design. A common example of random assignment is a medical trial in which a researcher assigns some participants at random to receive either a treatment drug or a placebo (a pill that looks like the medication but is known to be inert). Because of the random assignment, any differences that are observed in the outcome variable can, under certain assumptions, be causally attributed to the independent variable. Random assignment is not to be confused with random selection, which is the process by which researchers select a smaller sample from the larger population.

This entry discusses issues of causality, specifically how random assignment is used to help ensure that the observed differences between groups are due to the manipulated independent variable and not other preexisting differences between the groups. It also provides examples of different methods of randomly assigning participants to groups and describes the different levels of randomization, such as random assignment at the school level as opposed to the individual level. Finally, this entry discusses some potential problems that may arise with random assignment, particularly when one is working with human participants.

Causality and Internal Validity

The most important tenet of establishing causality between two variables is that there must be no other plausible explanation for the observed relationship between the variables. That is, in order to validly make the claim that independent variable A causes changes in outcome variable B, all other potential causes of changes in B must be ruled out. The many other potential variables that may affect the outcome variable are referred to as confounding variables or nuisance variables. If one is able to effectively rule out every other explanation for the relationship between variables A and B, the study has good internal validity. Randomly assigning participants to the various levels of the independent variable increases internal validity, and thus aids in establishing causation, because it helps create the “everything else equal” condition: The randomization process roughly equates the groups on every potential confounding variable. Thus, any differences observed between the groups over and above the small amount expected after random assignment must be due to the independent variable. The beauty of random assignment is that, if sample size is sufficiently large, it assures that all determinants of B, even unknown and unspecified ones, are largely evenly distributed between the groups.

Consider the following example of a researcher who is interested in the effects of an herbal medication on depression. From a pool of 100 depressed patients, the researcher randomly assigns half to receive the medication and the other half to receive a placebo pill. After 6 weeks, the researcher compares the levels of depression in the two groups. Because the researcher has randomly assigned participants to the two groups, any preexisting differences in the levels of depression, or any other possible confounding variable, should be approximately equated in these two groups. So if the difference in the levels of depression following treatment exceeds the small amount to be expected after randomization, the researcher can validly claim the difference is due to the medication.

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