Autism spectrum disorder denotes a group of developmental disabilities marked by impairments in social communication and restricted, repetitive patterns of behaviors and interests. Echolalia is quite common among those afflicted with the disorder. Although group designs have occupied a preeminent status in psychological research, the study used a single-case research design and applied learning principles to teach three words to an echolalic adult diagnosed with autism spectrum disorder. One of the advantages of using a single-case design methodology is that the participant served as his own control and was exposed to all training phases of the study. The case study also emphasizes the challenges of recruiting viable research participants and conducting research with people diagnosed with autism.