This is an ideal text for advanced courses in research methods and experimental design. It argues that the methodology of quantitative research is a unified discipline with basic notions, procedures and ways of reasoning which can be applied across the social, behavioural and life sciences. Key designs, models and methods in research are covered by leading contributors in their field who seek to explain the fundamentals of the research process to enable the student to understand the broader implications and unifying themes.

Clinical Trials: A Statistician's Perspective1

In this chapter, I will attempt a perspective on those methodological and practical developments in clinical trials that have made notable contributions to biostatistical and medical/public health knowledge.

My approach is non-technical and through themes of design, conduct, analysis, reporting, and interpretation I intend to guide the reader through a series of specific topics concentrating on the current state and future needs, with some historical reference. The list of topics is ...

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