Triple-Blind Studies

A triple-blind study is one in which participants, researchers, and analysts are unaware of whether the participant received the treatment or the placebo in a random assignment trial. Although a double-blind design leaves only the participants and researchers unaware of the treatment assignment, a triple-blind study additionally keeps the team analyzing the data from knowing which group’s data—placebo or treatment—it is evaluating. This design allows objectivity in the data collection phase and in the data analysis phase—analysts are able to evaluate data without any bias.


Barbara Henker and colleagues compared double- and triple-blind designs to examine a medication for hyperactivity in boys. They randomly assigned boys to one of two groups: the treatment group, which received the medication, and the placebo group, which received a placebo. ...

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