The institutional review board (IRB) is the oversight committee within an organization (e.g., a hospital or university) that ensures that all research conducted with human subjects is ethical, has an appropriate level of risk, and that participants in the study consent to be involved. This board ensures institutional compliance with federal standards for conducting ethical biomedical or behavioral research. To ensure institutional compliance, no research involving people can be conducted without approval of the IRB. Federal funding for research can be withdrawn if individuals or institutions do not comply with the federal guidelines for ethical conduct and the protection of research subjects. Thus, the IRB reviews research applications, [Page 708]can require modifications, approves or rejects proposed research plans, and continues to monitor all ...
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