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Sequential Analysis
During the past decade, various sequential design methods in clinical trial designs have been developed to allow for interim decisions and trial modifications based on cumulated information. As part of well-known adaptive designs in group sequential analysis, Yu Shen and Lloyd Fisher proposed a sequential strategy for monitoring clinical trials, namely self-designing trials. The final test statistic is a weighted average of the sufficient statistic from each stage, where the weight for each stage is determined by the observed data prior to that stage. One important feature of this self-designing trial is that the maximum sample size or the maximum number of interim analyses, m, is not specified in advance but at a random stopping time. The flexibility of modifying the sample size allows ...
- Descriptive Statistics
- Distributions
- Graphical Displays of Data
- Hypothesis Testing
- p Value
- Alternative Hypotheses
- Beta
- Critical Value
- Decision Rule
- Hypothesis
- Nondirectional Hypotheses
- Nonsignificance
- Null Hypothesis
- One-Tailed Test
- Power
- Power Analysis
- Significance Level, Concept of
- Significance Level, Interpretation and Construction
- Significance, Statistical
- Two-Tailed Test
- Type I Error
- Type II Error
- Type III Error
- Important Publications
- “Coefficient Alpha and the Internal Structure of Tests”
- “Convergent and Discriminant Validation by the Multitrait–Multimethod Matrix”
- “Meta-Analysis of Psychotherapy Outcome Studies”
- “On the Theory of Scales of Measurement”
- “Probable Error of a Mean, The”
- “Psychometric Experiments”
- “Sequential Tests of Statistical Hypotheses”
- “Technique for the Measurement of Attitudes, A”
- “Validity”
- Aptitudes and Instructional Methods
- Doctrine of Chances, The
- Logic of Scientific Discovery, The
- Nonparametric Statistics for the Behavioral Sciences
- Probabilistic Models for Some Intelligence and Attainment Tests
- Statistical Power Analysis for the Behavioral Sciences
- Teoria Statistica Delle Classi e Calcolo Delle Probabilità
- Inferential Statistics
- Q-Statistic
- R2
- Association, Measures of
- Coefficient of Concordance
- Coefficient of Variation
- Coefficients of Correlation, Alienation, and Determination
- Confidence Intervals
- Margin of Error
- Nonparametric Statistics
- Odds Ratio
- Parameters
- Parametric Statistics
- Partial Correlation
- Pearson Product-Moment Correlation Coefficient
- Polychoric Correlation Coefficient
- Randomization Tests
- Regression Coefficient
- Semipartial Correlation Coefficient
- Spearman Rank Order Correlation
- Standard Error of Estimate
- Standard Error of the Mean
- Student's t Test
- Unbiased Estimator
- Weights
- Item Response Theory
- Mathematical Concepts
- Measurement Concepts
- Organizations
- Publishing
- Qualitative Research
- Reliability of Scores
- Research Design Concepts
- Aptitude-Treatment Interaction
- Cause and Effect
- Concomitant Variable
- Confounding
- Control Group
- Interaction
- Internet-Based Research Method
- Intervention
- Matching
- Natural Experiments
- Network Analysis
- Placebo
- Replication
- Research
- Research Design Principles
- Treatment(s)
- Triangulation
- Unit of Analysis
- Yoked Control Procedure
- Research Designs
- A Priori Monte Carlo Simulation
- Action Research
- Adaptive Designs in Clinical Trials
- Applied Research
- Behavior Analysis Design
- Block Design
- Case-Only Design
- Causal-Comparative Design
- Cohort Design
- Completely Randomized Design
- Crossover Design
- Cross-Sectional Design
- Double-Blind Procedure
- Ex Post Facto Study
- Experimental Design
- Factorial Design
- Field Study
- Group-Sequential Designs in Clinical Trials
- Laboratory Experiments
- Latin Square Design
- Longitudinal Design
- Meta-Analysis
- Mixed Methods Design
- Mixed Model Design
- Monte Carlo Simulation
- Nested Factor Design
- Nonexperimental Design
- Observational Research
- Panel Design
- Partially Randomized Preference Trial Design
- Pilot Study
- Pragmatic Study
- Pre-Experimental Designs
- Pretest–Posttest Design
- Prospective Study
- Quantitative Research
- Quasi-Experimental Design
- Randomized Block Design
- Repeated Measures Design
- Response Surface Design
- Retrospective Study
- Sequential Design
- Single-Blind Study
- Single-Subject Design
- Split-Plot Factorial Design
- Thought Experiments
- Time Studies
- Time-Lag Study
- Time-Series Study
- Triple-Blind Study
- True Experimental Design
- Wennberg Design
- Within-Subjects Design
- Zelen's Randomized Consent Design
- Research Ethics
- Research Process
- Clinical Significance
- Clinical Trial
- Cross-Validation
- Data Cleaning
- Delphi Technique
- Evidence-Based Decision Making
- Exploratory Data Analysis
- Follow-Up
- Inference: Deductive and Inductive
- Last Observation Carried Forward
- Planning Research
- Primary Data Source
- Protocol
- Q Methodology
- Research Hypothesis
- Research Question
- Scientific Method
- Secondary Data Source
- Standardization
- Statistical Control
- Type III Error
- Wave
- Research Validity Issues
- Bias
- Critical Thinking
- Ecological Validity
- Experimenter Expectancy Effect
- External Validity
- File Drawer Problem
- Hawthorne Effect
- Heisenberg Effect
- Internal Validity
- John Henry Effect
- Mortality
- Multiple Treatment Interference
- Multivalued Treatment Effects
- Nonclassical Experimenter Effects
- Order Effects
- Placebo Effect
- Pretest Sensitization
- Random Assignment
- Reactive Arrangements
- Regression to the Mean
- Selection
- Sequence Effects
- Threats to Validity
- Validity of Research Conclusions
- Volunteer Bias
- White Noise
- Sampling
- Cluster Sampling
- Convenience Sampling
- Demographics
- Error
- Exclusion Criteria
- Experience Sampling Method
- Nonprobability Sampling
- Population
- Probability Sampling
- Proportional Sampling
- Quota Sampling
- Random Sampling
- Random Selection
- Sample
- Sample Size
- Sample Size Planning
- Sampling
- Sampling and Retention of Underrepresented Groups
- Sampling Error
- Stratified Sampling
- Systematic Sampling
- Scaling
- Software Applications
- Statistical Assumptions
- Statistical Concepts
- Autocorrelation
- Biased Estimator
- Cohen's Kappa
- Collinearity
- Correlation
- Criterion Problem
- Critical Difference
- Data Mining
- Data Snooping
- Degrees of Freedom
- Directional Hypothesis
- Disturbance Terms
- Error Rates
- Expected Value
- Fixed-Effects Model
- Inclusion Criteria
- Influence Statistics
- Influential Data Points
- Intraclass Correlation
- Latent Variable
- Likelihood Ratio Statistic
- Loglinear Models
- Main Effects
- Markov Chains
- Method Variance
- Mixed- and Random-Effects Models
- Models
- Multilevel Modeling
- Odds
- Omega Squared
- Orthogonal Comparisons
- Outlier
- Overfitting
- Pooled Variance
- Precision
- Quality Effects Model
- Random-Effects Models
- Regression Artifacts
- Regression Discontinuity
- Residuals
- Restriction of Range
- Robust
- Root Mean Square Error
- Rosenthal Effect
- Serial Correlation
- Shrinkage
- Simple Main Effects
- Simpson's Paradox
- Sums of Squares
- Statistical Procedures
- Accuracy in Parameter Estimation
- Analysis of Covariance (ANCOVA)
- Analysis of Variance (ANOVA)
- Barycentric Discriminant Analysis
- Bivariate Regression
- Bonferroni Procedure
- Bootstrapping
- Canonical Correlation Analysis
- Categorical Data Analysis
- Confirmatory Factor Analysis
- Contrast Analysis
- Descriptive Discriminant Analysis
- Discriminant Analysis
- Dummy Coding
- Effect Coding
- Estimation
- Exploratory Factor Analysis
- Greenhouse–Geisser Correction
- Hierarchical Linear Modeling
- Holm's Sequential Bonferroni Procedure
- Jackknife
- Latent Growth Modeling
- Least Squares, Methods of
- Logistic Regression
- Mean Comparisons
- Missing Data, Imputation of
- Multiple Regression
- Multivariate Analysis of Variance (MANOVA)
- Pairwise Comparisons
- Path Analysis
- Post Hoc Analysis
- Post Hoc Comparisons
- Principal Components Analysis
- Propensity Score Analysis
- Sequential Analysis
- Stepwise Regression
- Structural Equation Modeling
- Survival Analysis
- Trend Analysis
- Yates's Correction
- Statistical Tests
- F Test
- t Test, Independent Samples
- t Test, One Sample
- t Test, Paired Samples
- z Test
- Bartlett's Test
- Behrens–Fisher t′ Statistic
- Chi-Square Test
- Duncan's Multiple Range Test
- Dunnett's Test
- Fisher's Least Significant Difference Test
- Friedman Test
- Honestly Significant Difference (HSD) Test
- Kolmogorov-Smirnov Test
- Kruskal–Wallis Test
- Mann–Whitney U Test
- Mauchly Test
- McNemar's Test
- Multiple Comparison Tests
- Newman–Keuls Test and Tukey Test
- Omnibus Tests
- Scheffé Test
- Sign Test
- Tukey's Honestly Significant Difference (HSD)
- Welch's t Test
- Wilcoxon Rank Sum Test
- Theories, Laws, and Principles
- Bayes's Theorem
- Central Limit Theorem
- Classical Test Theory
- Correspondence Principle
- Critical Theory
- Falsifiability
- Game Theory
- Gauss–Markov Theorem
- Generalizability Theory
- Grounded Theory
- Item Response Theory
- Occam's Razor
- Paradigm
- Positivism
- Probability, Laws of
- Theory
- Theory of Attitude Measurement
- Weber–Fechner Law
- Types of Variables
- Validity of Scores
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