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In nested factor design, two or more factors are not completely crossed; that is, the design does not include each possible combination of the levels of the factors. Rather, one or more factors are nested within the levels of another factor. For example, in a design in which a factor (factor B) has four levels and is nested within the two levels of a second factor (factor A), levels 1 and 2 of factor B would only occur in combination with level 1 of factor A and levels 3 and 4 of factor B would only be combined with level 2 of factor A. In other words, in a nested factor design, there are cells that are empty. In the described design, for example, no ...

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